ME0328
- Product Name
- ME0328
- CAS No.
- 1445251-22-8
- Chemical Name
- ME0328
- Synonyms
- ME0328;ME0328 ME-0328;ME0328 USP/EP/BP;4-Dihydro-4-oxo-3;ME0328; ME 0328; ME-0328;4-Dihydro-4-oxo-N-[(1S)-1-phenylethyl]-2-quinazolinepropanamide;(S)-3,4-Dihydro-4-oxo-N-(1-phenylethyl)-2-quinazolinepropanamide;2-Quinazolinepropanamide, 3,4-dihydro-4-oxo-N-[(1S)-1-phenylethyl]-;(S)-3-(4-Oxo-3,4-dihydroquinazolin-2-yl)-N-(1-phenylethyl)propanamide;3,4-Dihydro-4-oxo-3,4-Dihydro-4-oxo-N-[(1S)-1-phenylethyl]-2-quinazolinepropanamide
- CBNumber
- CB82705099
- Molecular Formula
- C19H19N3O2
- Formula Weight
- 321.37
- MOL File
- 1445251-22-8.mol
ME0328 Property
- storage temp.
- Inert atmosphere,Store in freezer, under -20°C
- solubility
- DMSO: soluble10mg/mL, clear
- form
- powder
- color
- white to beige
- Stability:
- Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- SML0999
- Product name
- ME0328
- Purity
- ≥98% (HPLC)
- Packaging
- 5mg
- Price
- $119
- Updated
- 2024/03/01
- Product number
- SML0999
- Product name
- ME0328
- Purity
- ≥98% (HPLC)
- Packaging
- 25mg
- Price
- $527
- Updated
- 2022/05/15
- Product number
- 18488
- Product name
- ME0328
- Purity
- ≥98%
- Packaging
- 1mg
- Price
- $38
- Updated
- 2024/03/01
- Product number
- 18488
- Product name
- ME0328
- Purity
- ≥98%
- Packaging
- 5mg
- Price
- $85
- Updated
- 2024/03/01
- Product number
- 18488
- Product name
- ME0328
- Purity
- ≥98%
- Packaging
- 10mg
- Price
- $111
- Updated
- 2024/03/01
ME0328 Chemical Properties,Usage,Production
Description
The poly(ADP-ribose) polymerases (PARPs) are enzymes with roles in DNA repair, apoptosis, inflammation, and other cellular events, particularly in response to reactive oxygen and nitrogen species. ME0328 is an inhibitor of PARP3 (IC50 = 0.89 μM), which is a regulator of DNA repair and mitotic progression. It displays selectivity for PARP3 over 12 other PARP family members. ME0328 is cell permeable and elicits PARP3-specific effects at submicromolar concentrations.
Uses
ME0328 is a potent poly ADP ribose polymerase (PARP) inhibitor with selectivity towards the human ADP-Ribosyltransferase ARTD3/PARP3.
References
1) Lindgren?et al. (2013),?PARP Inhibitor with Selectivity Toward ADP-Ribosyltransferase ART3/PARP3; ACS Chem. Biol.,8?1689
ME0328 Preparation Products And Raw materials
Raw materials
Preparation Products
ME0328 Suppliers
- Tel
- 857-239-0968
- Fax
- 857-239-8801
- service1@targetmol.com
- Country
- United States
- ProdList
- 2559
- Advantage
- 60
- Tel
- +1-708-310-1919 +1-13798911105
- Fax
- 708-557-7486
- sales@invivochem.cn
- Country
- United States
- ProdList
- 6393
- Advantage
- 58
- Tel
- +1-833-552-7181
- sales@aladdinsci.com
- Country
- United States
- ProdList
- 57511
- Advantage
- 58
- Tel
- +1-781-999-5354
- support@targetmol.com
- Country
- United States
- ProdList
- 19973
- Advantage
- 58
View Lastest Price from ME0328 manufacturers
- Product
- ME0328 1445251-22-8
- Price
- US $1.00/g
- Min. Order
- 1g
- Purity
- 99%
- Supply Ability
- 200kg
- Release date
- 2019-12-25